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Table 3 Univariate and multivariate analysis of factors influencing stone recurrence after ESWL treatment

From: Post-ESWL urinary osteopontin level and ion-activity product of calcium oxalate are associated with stone recurrence after 5-year follow-up

Parameters

Univariate

Multivariate

OR

95% CI

p value

OR

95% CI

p value

2 weeks post- ESWL

      

 αGST

4.58

0 0.99–21.12

0.051

   

 πGST

4.40

0.98–19.85

0.054

   

 AP CaOx

4.58

0.99–21.12

0.051

   

 MDA

3.54

0.78–16.03

0.102

   

 HA

3.33

0.76–14.58

0.110

   

 NPC

0.52

0.12–2.17

0.368

   

 NRP

3.33

0.76–14.58

0.110

   

 SLC26A6

4.58

0.99–21.12

0.051

   

 CXCR4

4.40

0.98–19.85

0.054

   

 MMP2

3.3

0.75–14.47

0.113

   

 MMP9

4.4

0.98–19.85

0.054

   

 OPN

6.05

1.27–28.73

0.024*

18.61

0.81–426.9

0.067

 THP

0.86

0.21–3.58

0.833

   

4 weeks post-ESWL

      

 αGST

0.89

0.22–3.67

0.870

   

 πGST

0.52

0.12–2.17

0.368

   

 AP CaOx

60.7

2.58–659.3

0.023*

36.53

1.81–737.4

0.019*

 MDA

1.56

0.36–6.69

0.553

   

 HA

0.89

0.22–3.67

0.870

   

 NPC

1.50

0.36–6.23

0.577

   

 NRP

2.50

0.59–10.62

0.214

   

 SLC26A6

5.14

1.03–25.60

0.046

3.33

0.27–41.92

0.352

 CXCR4

6.05

1.27–28.73

0.024

6.81

0.41–115.7

0.184

 MMP2

0.88

0.21–3.59

0.853

   

 MMP9

0.88

0.21–3.59

0.853

   

 OPN

8.67

1.66–45.21

0.010*

13.55

1.75–243.5

0.047*

 THP

2.57

0.60–11.06

0.204

   
  1. Abbreviations: ESWL, extracorporeal shock wave lithotripsy; OR, odds ratio; CI, confidence interval; APCaOx, ion-activity product of calcium oxalate; MDA, malondialdehyde; GST, glutathione S-transferase; HA, hyaluronic acid; NPC, nuclear pore complex p62; NRP, nucleolin-related protein; OPN, osteopontin; THP, Tamm-Horsfall protein; SLC26A6, solute carrier family 26 member 6 (oxalate transporter); CXCR4, C-X-C chemokine receptor type 4; MMP, matrix metalloproteinase; πGST, pi-glutathione S-transferase; αGST, alpha-glutathione S-transferase