Table 1 Patient and disease characteristics
From: Chronic renal impairment predicts oncological outcomes in UTUC patients undergoing RNU
| Â | Non-CKD | CKD | P value | ||
|---|---|---|---|---|---|
N | %/IQR | N | %/IQR | Â | |
Number of patients, % | 875 | 62.4% | 528 | 37.6% | Â |
Median age, IQR | 68.0 | 13.0 | 74.0 | 13.0 | 0.02 |
Gender, % | |||||
 Male | 631 | 72.1% | 381 | 72.2% | 0.487 |
 Female | 244 | 27.9% | 149 | 27.8% |  |
Median BMI (m2/kg), IQR | 25.6 | 4.9 | 25.1 | 5.2 | 0.07 |
Preoperative eGFR (mL/min/1.73 m2) |  |  |  |  | < 0.001 |
 Mean, SD | 78.6 | 16.9 | 43.9 | 12 |  |
 Median, IQR | 75.0 | 25.0 | 46.0 | 14.5 |  |
Median Charlson comorbidity score, IQR | 4 | 2–6 | 5 | 3–8 | < 0.001 |
Significant cardiovascular disease, % | 101 | 11.5% | 95 | 18.0% | 0.06 |
History of smoking, % | 533 | 60.9% | 289 | 54.7% | 0.02 |
ASA, % | |||||
 1 | 129 | 14.7% | 49 | 9.3% | < 0.001 |
 2 | 469 | 53.6% | 232 | 43.9% |  |
 3+ | 262 | 29.9% | 243 | 46.0% |  |
 Missing | 15 | 1.7% | 10 | 1.9% |  |
History of bladder cancer. % | 143 | 16.3% | 90 | 17.0% | 0.767 |
Surgical approach, % | |||||
 Open | 315 | 36.0% | 171 | 32.4% | 0.505 |
 Laparoscopic or robotic | 560 | 64.0% | 357 | 67.6% |  |
Tumour laterality, % | |||||
 Left | 428 | 48.9% | 258 | 48.9% | 0.496 |
 Right | 447 | 51.1% | 270 | 51.1% |  |
Tumour location,% | |||||
 Ureter only | 211 | 24.1% | 140 | 26.5% | 0.447 |
 Renal pelvis only | 426 | 48.7% | 242 | 45.8% |  |
 Multifocal | 94 | 10.7% | 51 | 9.7% |  |
 Missing | 144 | 16.5% | 95 | 18.0% |  |
Tumour grading, % | |||||
 Grade 1 | 116 | 13.3% | 38 | 7.2% | < 0.001 |
 Grade 2 | 215 | 24.6% | 118 | 22.3% |  |
 Grade 3 | 435 | 49.7% | 303 | 57.4% |  |
 Missing | 109 | 12.5% | 69 | 13.1% |  |
pT stage, % | |||||
 Ta/is | 173 | 20.9% | 86 | 16.3% | 0.125 |
 T1 | 178 | 20.3% | 96 | 18.2% |  |
 T2 | 169 | 19.3% | 95 | 18.0% |  |
 T3 | 242 | 27.7% | 180 | 34.1% |  |
 T4 | 36 | 4.1% | 27 | 5.1% |  |
 Missing | 77 | 8.8% | 44 | 8.3% |  |